Intraspinal microstimulation preferentially recruits fatigue-resistant muscle fibres and generates gradual force in rat
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چکیده
منابع مشابه
Muscle synergies evoked by microstimulation are preferentially encoded during behavior
Electrical microstimulation studies provide some of the most direct evidence for the neural representation of muscle synergies. These synergies, i.e., coordinated activations of groups of muscles, have been proposed as building blocks for the construction of motor behaviors by the nervous system. Intraspinal or intracortical microstimulation (ICMS) has been shown to evoke muscle patterns that c...
متن کاملReanimating the arm and hand with intraspinal microstimulation.
To date, there is no effective therapy for spinal cord injury, and many patients could benefit dramatically from at least partial restoration of arm and hand function. Despite a substantial body of research investigating intraspinal microstimulation (ISMS) in frogs, rodents and cats, little is known about upper-limb responses to cervical stimulation in the primate. Here, we show for the first t...
متن کاملModularity of motor output evoked by intraspinal microstimulation in cats.
We studied the forces produced at the cat's hindpaw by microstimulation of the ipsi- and contralateral lumbar spinal cord in spinal intact alpha-chloralose anesthetized (n = 3) or decerebrate (n = 3) animals. Isometric force and EMG responses were measured at 9-12 limb configurations, with the paw attached to a force transducer and with the hip and femur fixed. The active forces elicited at dif...
متن کاملReturning Independence to the Paralyzed: Intraspinal Microstimulation Prosthetics
University of Pittsburgh, Swanson School of Engineering 11.01.2016 1 Disclaimer—This paper partially fulfills a writing requirement for first year (freshman) engineering students at the University of Pittsburgh Swanson School of Engineering. This paper is a student, not a professional, paper. This paper is based on publicly available information and may not provide complete analyses of all rele...
متن کاملMRI-Guided Stereotactic System for Delivery of Intraspinal Microstimulation.
STUDY DESIGN Laboratory/animal-based proof of principle study. OBJECTIVE To validate the accuracy of a magnetic resonance imaging (MRI)-guided stereotactic system for intraspinal electrode targeting and demonstrate the feasibility of such a system for controlling implantation of intraspinal electrodes. SUMMARY OF BACKGROUND DATA Intraspinal microstimulation (ISMS) is an emerging preclinical...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2005
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2005.094516